Calogera M Simonaro Selected Research

Pentosan Sulfuric Polyester (Pentosan Polysulfate)

12/2019	Safety Study of Sodium Pentosan Polysulfate for Adult Patients with Mucopolysaccharidosis Type II.
1/2019	Pentosan Polysulfate Treatment of Mucopolysaccharidosis Type IIIA Mice.
1/2016	Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs.
1/2014	Dose responsive effects of subcutaneous pentosan polysulfate injection in mucopolysaccharidosis type VI rats and comparison to oral treatment.
1/2013	Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses.

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Calogera M Simonaro Research Topics

Disease

12	Mucopolysaccharidoses 12/2019 - 05/2005
5	Inflammation (Inflammations) 01/2021 - 01/2008
3	Farber Lipogranulomatosis 06/2017 - 02/2002
3	Joint Diseases (Joint Disease) 08/2014 - 01/2008
3	Niemann-Pick Diseases (Niemann Pick Disease) 02/2013 - 05/2006
2	Mucopolysaccharidosis I (Hurler Syndrome) 01/2016 - 08/2014
2	Mucopolysaccharidosis VI (Syndrome, Maroteaux-Lamy) 01/2014 - 01/2011
2	Congenital Abnormalities (Deformity) 01/2013 - 01/2011
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2021
1	Reperfusion Injury 01/2021
1	Necrosis 01/2021
1	Neuroinflammatory Diseases 12/2019
1	Mucopolysaccharidosis II (Hunter Syndrome) 12/2019
1	Neurologic Manifestations (Neurological Manifestations) 12/2019
1	Mucopolysaccharidosis III (Sanfilippo Syndrome) 01/2019
1	Spinal Cord Compression 08/2014
1	Protein Deficiency 01/2013
1	Malocclusion (Crossbite) 01/2013
1	Sphingolipidoses (Sphingolipidosis) 01/2013
1	Connective Tissue Diseases (Connective Tissue Disease) 01/2008
1	Bone Diseases (Bone Disease) 05/2005
1	Type B Niemann-Pick Disease 12/2002

Drug/Important Bio-Agent (IBA)

5	Pentosan Sulfuric Polyester (Pentosan Polysulfate)FDA Link 12/2019 - 01/2013
5	GlycosaminoglycansIBA 01/2016 - 05/2005
4	Acid CeramidaseIBA 01/2021 - 02/2002
4	neodymium pyrocatechin disulfonate (NPD)IBA 02/2013 - 12/2002
3	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 02/2013 - 05/2006
3	AcidsIBA 02/2013 - 05/2006
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013 - 01/2010
2	SphingolipidsIBA 01/2021 - 01/2013
2	CytokinesIBA 01/2019 - 05/2005
2	CeramidesIBA 06/2017 - 06/2013
2	HydrolasesIBA 01/2013 - 05/2006
2	Toll-Like Receptor 4IBA 01/2011 - 01/2010
1	EndocannabinoidsIBA 01/2021
1	Prednisone (Sone)FDA LinkGeneric 08/2014
1	N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B)IBA 04/2013
1	Dermatan SulfateIBA 04/2013
1	SphingomyelinsIBA 02/2013
1	Tissue Inhibitor of Metalloproteinase-1IBA 01/2013
1	MineralsIBA 01/2013
1	EnzymesIBA 01/2013
1	ADAMTS5 ProteinIBA 01/2013
1	Infliximab (Remicade)FDA Link 01/2010
1	Therapeutic UsesIBA 01/2010
1	Pharmaceutical PreparationsIBA 01/2010
1	LipidsIBA 05/2006
1	Biomarkers (Surrogate Marker)IBA 05/2005
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2005
1	Matrix Metalloproteinases (MMPs)IBA 05/2005
1	CeramidasesIBA 02/2002

Therapy/Procedure

5	Enzyme Replacement Therapy 06/2017 - 01/2010
4	Therapeutics 12/2019 - 01/2011
1	Subcutaneous Injections 01/2016
1	Hematopoietic Stem Cell Transplantation 08/2014